Orthopaedic Oncology: Review Questions

Questions 1 and 2 refer to the following case. A 21-year-old man presents with worsening right knee pain after a minor twisting injury playing basketball 3 months ago. The patient reports increased swelling along the posterior aspect of his knee and generalized leg edema on the right side. His pain is exacerbated by weight-bearing activities and deep knee flexion. The patient denies night pain, fevers, chills, or recent weight loss. His past medical history is significant for unilateral retinoblastoma, which was treated with minimal residual visual deficit. A technetium bone scan depicts an isolated lesion located in the right distal femur, and magnetic resonance imaging (MRI) shows sparing of the neurovascular bundle. A plain radiograph of the distal femur is shown in Figure 1.